A Rare Case of Pneumonia Evolving into Atypical Haemolytic Uremic Syndrome

Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterised by non-immune haemolytic anaemia, thrombocytopenia and acute kidney injury. It results from chronic, uncontrolled activation of the alternative complement pathway, leading to thrombotic microangiopathy (TMA). Renal impairment and progression to end-stage renal disease are common in untreated patients with aHUS. We report a case of 60year old who was initially treated for pneumonia and acute kidney injury and was later diagnosed with atypical haemolytic anaemia based on clinical and lab parameters. The patient was successfully treated by plasma exchange which is the treatment of choice for HUS.