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Tuberous sclerosis with bilateral renal cell carcinoma in a child: A case report

Journal: Pediatric Urology Case Reports (Vol.2, No. 1)

Publication Date:

Authors : ; ; ; ;

Page : 1-6

Keywords : Tuberous sclerosis complex; renal cell carcinoma; children; tuberin; hamartin;

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Tuberous sclerosis complex (TCS) is an autosomal dominant disease which comes under a group of diseases known as neurocutaneous syndrome. Incidence of TCS is around 1 in 6000. The clinical triad of papular facial nevus, seizures and mental retardation is found in less than 50% of the patients. Renal lesions in TCS commonly consist of simple renal cyst and angiomyolipomas. Renal cell carcinoma though rarely associated with tuberous sclerosis may be its significant manifestations. We report a case of TCS with bilateral renal cell carcinoma in a 12 year old child with classical radiological and clinical signs.

Last modified: 2014-12-30 01:30:04