Mortality in Emergency Department Sepsis Score (MEDS): Predictive Accuracy and Feasibility for 28-Day Mortality of Patients with Sepsis in an Indian Emergency Department

OBJECTIVES: (1) To assess the ability of MEDS score to predict mortality in septic patients treated with modified EGDT. (2) To find out the clinical profile of the patients presenting to emergency department in severe sepsis& septic shock. MATERIALS AND METHODS: This is a prospective study conducted in Kempegowda Institute of Medical Sciences and Research Centre, Bengaluru, India. The study was carried out in the period of November 2014 to September 2016 and 50 patients were included in the study. The detailed history, clinical examination and all the relevant laboratory investigations were done including blood culture. In the present study, the conditions were defined according to standard practice and based on relevant literature. All the patients of sepsis admitted to ICU/ emergency ward were prognosticated on the basis of MEDS score. We have analyzed various profiles between two groups ; survivor group which include the patients who are successfully discharged after recovery and non-survivor group which include the patients who died. RESULTS: The clinical profile of 50 patients with sepsis with septic shock were treated with modified EGDT were studied. There were 26 males and 24 females in this cohort. In our study, 16 patients died and 34 patients survived for an in-hospital mortality of 32.0 %. . In this study, mean MEDS score was high among non survivors than survivors ( (16.31 vs 9.15), it was very much statistically significanct (p=