Investigation of Ethanol Soluble Bioactive Compounds in Tender Fruits of Thespesia Populnea

Hot and cold extracts of tender fruits of Thespesia populnea were made in ethanol and evaluated against ten Gram positive and Gram negative human bacteria by Agar cup method. Both the extracts were effective against Bacillus subtilis, Streptococcus pyogens, Corynebacterium diphtheriae and Klebseilla pneumonia whereas Pseudomonas aeruginosa was susceptible to only cold extract. Minimum Inhibitory Concentrations (MIC) of cold and hot extracts, Activity guided fractionations showed comparable antimicrobial activity with antibiotics, Gentamicin (G-10mcg) and Ampiclox (ACX-20mcg).