Prevalence of Dengue in Patna District in Bihar

BACKGROUND Dengue virus is a single stranded RNA virus of family Flaviviridae. It is transmitted by Aedes mosquito, particularly Aedes aegypti. It is distributed worldwide but epidemic is more prevalent in tropics and subtropics. Dengue is usually a flue like illness but may cause life threatening complications like dengue hemorrhagic fever and dengue shock syndrome. Four serotypes of dengue virus are prevalent worldwide (DEN-1, DEN-2, DEN-3, and DEN-4). OBJECTIVES To study the diagnosis of dengue by antigen and antibody detection test and to detect the prevalence rate of dengue by age wise and sex wise distribution. METHODS A prospective study of 526 patients was done based on clinical criteria of dengue. RESULT Among 526 serum samples, 84 samples were found positive by NS1 Ag MICROELISA, IgM MICROELISA& IgG MICROELISA tests, of various samples. CONCLUSION prevalence of dengue in Patna district of Bihar is estimated on the basis of serological investigations in this study.