Synthesis, Characterization, Biological Activity and Use of Thiourea Derivative ( PhTTU ) Studies of dinitrate-1-phenyl-3-(thiazol-2-yl)-2-thioureato Cd(II) ion Complex

In this study a complex of the general formula Cd (PhTTU) 2 (NO3) 2, ( PhTTU is 1-phenyl-3- (thiazole-2-yl) -2-thiourea), was synthesized in two steps starting with the reaction of 2-amino thiazol with phenyl isothiocyanate then followed by the addition of PhTTU ligand. Initial characterization based on the elemental analysis has suggested one possible structure (scheme 1). This ligand as one of the thiourea derivatives was successfully synthesized. The ligand was characterized by IR, NMR and CHN elemental analysis. The complex was characterized by elemental analysis and melting point. Although, both PhTTU ligand and the cadmium complex showed antimicrobial activities, the complex inhibition to the studied microorganisms was higher.