Correlation between Optic Disc Damages and Functional Glaucoma Changes

Glaucoma leads to morphologic changes of the optic nerve head and to functional defects. Morphologic changes in the three-dimensional surface structure of the optic nerve head at its entrance site into the globe can be examined by OCT. The aim of this study is to examine aspects of the correlation between structural and functional changes of the optic nerve head (ONH). This was a prospective study. One hundred six eyes of 53 patients with glaucoma who were followed up during the period from 2013 to 2014 were included at Ungjillezimi Clinic in Tirana, Albania. We analysed the data of 106 eyes (53 patients, mean age 65.7 12.4 years, mean baseline MD) 7.1 5.1). The most common progression parameters were neuroretinal rim change (73 %), followed by PPA enlargement (42 %), DH detection (27 %) and enlargement of a RNFL defect. Structural changes may be more prominent at earlier stages of glaucoma, while functional changes may be more prominent at more advanced disease stages.