Efficacy of Hyaluronidase in Enhancing the Effect of Inferior Alveolar Nerve Block when Used in Conjugation with Lidocain

Aim Present study was conducted to check the effiacy of hyaluronidase in enhancing the effect of inferior alveolar nerve block when used in conjugation with lidocain. Methods Patients diagnosed with irreversible pulpitis jn mandibular molar were selected for the study. After noting the baseline stimulus on premolars by electronic pulp tester, inferior alveolar nerve blocj was injected. Thirty minutes after the onset of anesthesia, placebo and hyaluronidase was injected during the control and test phases of the study respectively. Duration of anesthesia was recorded with help of electronic pulp tester on the premolar and by the needle prick on the gingiva. Results Significant increase in the duration of pulpal and gingival anesthesia was observed by administering hyaluronidase after the lidocain injection. Conclusion Hyaluronidase when used before the end of anesthesia effect of lidocain in inferior alveolar nerve block can increase the efficacy of anesthetic.