Histopatthological Changes in Liver of Albino Rat Induced by Experimental Infection of A. lumbricoides

Ascarislumbricoidesis a gastrointestinal parasite infects the digestive tracts of humans, causing Ascariasis, and is estimated to infect approximately 1.4 billion persons on a global basis. During the following investigations various immunopathological changes were observed in low and high doses of infection. Changes were evident in hepatic cells, sinusoids, central and portal vein. These were cloudy swelling, fatty cyst formation, kupffer cell hyperplasia and inflammation. In the present studies kupffer cell hyperplasia, focal collections of lymphocytes were observed in high dose of sixty days of post-infection.