Some Biochemical and Haematological Studies on the Effect of Black seed and Curcumin in Vaccinated Broiler with Gumboro

This study was carried out to investigate the adverse effects of Gumborovaccine on performances, immunity and some biochemical parmeter of Broiler chicks. A total 120 broiler chicks were used in this study and divided into 6 groups each group contain 20 chicken and all chicks were weighted weekly till the end of the experiment. The results showed the broiler treated with Nigella sativa and curcumin produce increase in B. W, TLC andlymophcyte while decrease in neutrophil percent. Nigella sativa and curcumin induced increase in TP, Albumin, although NS and curcumin groups showed a significance decrease in ALT and AST, significantly increase in SOD, GSH, CAT and significantly decrease in MDA. Gumboro vaccine induced hepatic disorders and immunosuppressive revealed by decrease B. W, total Leucocytic countand lymophcyte percent, while increase in neutrophil percent. Gumboro vaccine induced decrease in total protein, Albumin, globulin increase in alanine aminotransferase (ALT) and Aspartate aminotransferase (AST), decrease in SOD, GSH, CAT, and significantly increase in MDA. This study indicated that treatment with Nigella sativa and Curcumin improved the adverse effects of Gumboro vaccine on performances, immunity, some biochemical parameters in serum and tissues, also decrease the risk of exposure to Gumboro vaccine, improve both of general health condition and immunostatus of chicks. Black seed, Curcumin, Broiler, Gumboro vaccine