A Study of Relation of Propofol Dose to Attain Induction in Anesthesia when used with Dexmedetomidine

Since a combination of propofol and dexmedetomidine can cause both beneficial and adverse effects on the patient, it would be ideal to titrate the dosage of dexmedetomidine to retain its desirable effects while negating its side effects. Different doses of dexmedetomidine have been used with an induction agent for attenuation of hemodynamic response to intubation. Dexmedetomidine a potent, highly selective 2 adrenoreceptor agonist possess desirable properties like sedation, analgesia, sympatholysis and reduces the anaesthetic requirement.