POSSÍVEIS HIPÓTESES ASSOCIADAS À OCORRÊNCIA DE COVID-19 EM INDIVÍDUOS JOVENS IMUNOCOMPETENTES: DESAFIOS CONTEMPORÂNEOS PARA A SAÚDE PÚBLICA E SAÚDE COLETIVA

The SARS-CoV-2 virus was identified primarily in the city of Wuhan, located in China, in December 2019. Since then, the virus has spread across the world, and consequently the scenario of pandemic has been established, been officialized in March, 11, 2020. Thus, infections by SARS-Cov-2 became a severe problem of world health, with thousands of deaths across the globe. The disease caused by a virus infection seems to be severe in patients with immune deficiency, although patients immune competent also develop the critical ways of the disease and die. The main focus of this work is to introduce hypothesis that may be correlated with the severe manifestations of COVID-19 in young and immune competent patients, through a review. For the execution of this work it was made a literary review about the theme COVID-19, thought publications indexed in the main database of free access available on the internet. The results suggest that several factors are related with the critical manifestations of COVID-19, being them the immune response of the host, the thrombus formations, immune complexes, life habits and genetic conditions. And so, it is concluded that SARS-CoV-2 infection can evolve to the most severe forms of the disease in young immuncompetent individuals, according to the location of the viral infection, lifestyle, the formation of immune complexes and genetic factors. In addition, it is evident the need to develop new research so that these hypotheses are validated or not.