Medicated Chewing Gum- A Patient Friendly Oromucosal Drug DeliveryJournal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.6, No. 7)
Publication Date: 2021-07-30
Authors : Bhushan Mali; P. B. Patil; R. S. Bachhav;
Page : 128-152
Keywords : Medicated chewing gum; patient convenience; Bioavailability; Oromucosal absorption;
Over the years, simplification of patients and patient-centered research in the field of drug delivery has led to the emergence of new drug delivery options. In them, chewing gum (MCG) had the means to give the simplest medicine, not only to special groups with problems of swallowing like children and the elderly, but also to all people, including the younger generation. The chewing gum contains a thin layer of masticatory gum coating that can be a film of polymers, waxes, sugar, flavors, or colors. A chemical ingredient can be present in the core, in the coating, or in both. The level of oromucosal absorption depends on the condition of the mucosa, the time of contact, and the physicochemical characteristics of the active ingredient. A small non-lipophilic molecule dissolved in enzymatic stable solids is more likely to penetrate. In the case of local action, it is possible to achieve beneficial results with a medicated chewing gum higher than that obtained by troches. Patients in particular may view chewing gum as the preferred method of drug management compared to oral drinks or pills. The use of herbal remedies is possible as a local treatment for oral diseases and treatment of systemic conditions.
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Last modified: 2021-08-03 19:11:06