A Comparative Study of Variations of Lipid Profile in Patients of Chronic Kidney Disease and the Controls Coming to Pravara Rural Hospital, Loni

Background and Objective: Chronic kidney disease patients were found to have varied lipid profiles depending on the co - morbid conditions and also the treatment given. The lipid profiles of these patients in the western and the Indian subcontinent are widely varied in different studies. This study was undertaken to compare the lipid profile in CKD patients and healthy individuals in Pravara Rural Hospital, Loni, Ahmednagar. Method: This study was a comparative study which had been done over a period of two years in 40 patients with CKD (STAGE V - undergoing hemodialysis) vs.40 as control group which were AGE and SEX matched. The lipid profile was studied on these patients. Results: The mean value of serum triglycerides, total cholesterol and LDL was significantly higher than control group. HDL, VLDL was significantly lower than control group. The mean value of serum triglycerides, total cholesterol and LDL was highest in patients whose serum urea was greater than140mg/dL. The mean value of serum triglycerides, total cholesterol was higher in patients whose serum creatinine was greater than8 mg/dL. Conclusion: Significant amount of change in lipid profile was found in patients of CKD, hence it is worth while detecting and treating hyperlipidemia in chronic renal failure patients early on.