Genetic Influence on Open Bite: A Case Report

Open bite is one of the most serious malocclusions that can affect a patient's masticatory processes, it is also a condition that is poorly known and investigated. The majority of recorded instances are sporadic or idiosyncratic, with a wide range of etiologies that are still poorly understood. Although open bite has been linked to primary failure of eruption (PFE), lateral tongue push, and medical syndromes or temporomandibular joint dysfunction, the intricate interplay of environmental and genetic factors makes its ethiopathogenesis a challenging issue to comprehend and explore. Further research into the gene(s) and mechanism(s) involved can not only help us better comprehend open bite and the complex muscular-occlusal link, but it can also help us figure out the best ways to treat these (and possibly other) malocclusions.