Hepatic Adenomas Challenges to their Diagnosis and Management with Emphasis on the Bordeaux Classification | Biomedgrid

It has been postulated that disrupted hepatic vasculature results in the development of hepatic lesions including hepatic adenomas, FNH, and hemangiomas. The etiology of HA is that an altered hepatic circulation stimulates the evolution of hepatic adenomas, FNH and hemangiomas. The stimuli provided by estrogen and anabolic steroids in the genesis of HA is well established and first recognized by Edmundson. They can result from abnormal carbohydrate metabolism such as: in glycogen storage disease, mature onset diabetes mellitus of the young type 3 (MODY3), and metabolic syndrome. Other factors include Anabolic steroids exposure, Fanconi Anemia, glycogen storage disease types I, III and IV, and familial adenomatous polyposis.