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VITAMIN D AS A PROMISING ANTICANCER AGENT P. Shabana*, K. Saipriya, Abbaraju Lakshmi Harini, Pusuluri Dharani Lakshmi Sai, Konkipudi Venkata Sivaiah, Brahmaiah Bonthagarala

Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.2, No. 3)

Publication Date:

Authors : ; ; ; ; ; ;

Page : 705-713

Keywords : vitamin D; cancer; angiogenesis; steroid hormone;

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Abstract: Vitamin D is the steroid vitamin it is a group of fat soluble vitamin it helps in absorption and metabolism of calcium and phosphorous. It is a well-known essential vitamin for bone health it is mainly circulating in blood and regulating the activities of various cell types its main significances is the maintenance of plasma ca2+concentration. It plays a beneficial role in genesis progression and survival of cancerous growths. It mainly interferes with the various growth factors by inhibiting the proliferation of the cells angiogenesis and facilitation of the cell differentiation and apoptosis. It is not a primary anticancer agent but it poses antitumor and anti metastatic properties it may used in the treatment of cancer as a adjuvant Key words: vitamin D, cancer, angiogenesis, steroid hormone

Last modified: 2015-03-30 21:57:55