The Study of Hypothyroidism in Pregnant Women and It's Effect on Maternal and Fetal Outcome

Objective: To study the impact of maternal hypothyroidism on maternal and foetal outcome. Study Design: The study was conducted for the duration of 6 months from 17/8/20 to 10/3/21. Pregnant women with hypothyroidism who came for ANC check up to OBG Department, MMC and RI, Mysuru irrespective of gestational age, form the source of data. Results: In our study, subclinical hypothyroidism was associated with complications like PE (24%), Abruptio Placenta (1%), anaemia (12.5%), Abortion (4.8%), PPH (1.9%), preterm (8.65%), IUGR (13.46%), respiratory distress (27.88%), IUD (1.92%). overt hypothyroidism was associated with complications like PE (39.3%), Abruptio Placenta (7%), anaemia (17.9%), abortion (17.9%), PPH (3.6%), PTD (10.71%), IUGR (10.71%), RD (39.28%) and IUD (7.14%). Hypothyroid pregnant women in euthyroid state had complications like PE (14%), anemia (8%), PPH (2%), IUGR (14%), respiratory distress (10%) and IUD (2%). Conclusion: In our study, subclinical hypothyroidism was associated with complications like PE (24%), abruptio placenta (1%), anaemia (12.5%), abortion (4.8%), PPH (1.9%), PTD (8.65%), IUGR (13.46%), respiratory distress (27.88%) and IUD (1.92%). Overt hypothyroidism was associated with complications like PE (39.3%), abruptio placenta (7.1%), anaemia (17.9%), abortion (17.9%), PPH (3.69%), PTD (10.71%), IUGR (10.71%), respiratory distress (39.28%) and IUD (7.14%). Hypothyroid pregnant women in euthyroid state had complications like PE (14%), anaemia (8%), PPH (2%), IUGR (14%), respiratory distress (10%) and IUD (2%), emphasizing the importance of routine antenatal thyroid screening in first trimester. This study re-emphasizes that the requirement of close surveillance of thyroid status to maintain euthyroidism and intensive foetal monitoring during pregnancy to achieve good maternal and perinatal outcome.