A Comparative Study of Perinatal Outcome in Women with Pre-Eclampsia Using Cerebroplacental Ratio of Fetal Middle Cerebral Artery and Umbilical Artery on Doppler Ultrasound

We conducted an observational prospective study from May 2018 to October 2019 in which Doppler Ultrasonography was done in 100 Antenatal women with pre-eclampsia, beyond 34 weeks of gestation. Based on cerebroplacental ratio patients were divided into two groups: 1. cerebroplacental ratiogreater than/=1, 2. cerebroplacental ratio less than1. There were 65 cases with a CPR greater than1 and 35 with CPRless than1. More women with CPR less than1 required caesarean section (85.7%), developed IUGR (85.7%), required early termination with average gestational age at termination being 36.1 weeks, had low birth weight babies, mean birth weight being 2208g, thus higher number of babies required NICU care (71.4%). In women with CPRgreater than1, caesarean section rate was 46.2%, average age for termination of pregnancy was 37.4 weeks, mean birth weight 2426 g with 30.5% fetuses developing IUGR and 30.5 % neonates requiring NICU care. Our study showed that women with CPR less than1 had higher chances of development of IUGR and undergoing caesarean section. They required preterm termination of pregnancy and had low birth weight babies who needed NICU care. There were no still births or neonatal deaths indicating that timely intervention in delivering a woman with pre-eclampsia with changes on Doppler ultrasound can prevent adverse neonatal outcomes.