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Journal: Journal of the Grodno State Medical University (Vol.20, No. 2)

Publication Date:

Authors : ;

Page : 182-186

Keywords : physiological pregnancy; pregnancy loss; pro-inflammatory markers;

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The medical and socio-economic significance of the problem of early reproductive losses is determined by a decrease in the birth rate and a deterioration in the demographic situation. Purpose of the study: To evaluate the diagnostic significance of some laboratory parameters characterizing the inflammatory response and their role in early pregnancy losses. Material and methods. Blood serum, medical records, prenatal records of 94 women. The study of interleukin-6 and tumor necrosis factor-alpha was carried out using enzyme immunoassay. The level of white blood cells, banded neutrophils, segmental leukocytes, eosinophils, basophilis, monocytes, lymphocytes and erythrocyte sedimentation rate was determined by general clinical routine methods. Results. Interleukin-6 in combination with segmental leukocytes, monocytes, erythrocyte sedimentation rate can indicate the formation of pro-inflammatory cascade and can trigger abortion mechanisms.

Last modified: 2022-05-26 22:29:17