Importance of Lowered Ionized Magnesium Concentrations in Elderly Hypertensives | Biomedgrid

In recent publications a magnesium deficiency in elderly is up to 50%, depending on co-morbidity, drugs and nutritional status [1, 2]. On the other hand, it is well known that a magnesium insufficiency is a pathogenic factor in the development of primary hypertension [2, 3, 4, 5, 6, 7]. In this context calcium magnesium antagonism, sodium magnesium antiport, disturbed vitamin D metabolism or disturbed magnesium channels (TRPM 6 and 7) are of special interest [2, 3, 4, 5, 6, 7]. For these reasons magnesium metabolism was of interest in elderly hypertensives. Ionized magnesium is the active form and was measured additionally. Up to now it is not clear whether there is a correlation between plasma or serum magnesium concentrations and ionized magnesium content.