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Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.9, No. 2)

Publication Date:

Authors : ; ; ;

Page : 36-51

Keywords : Solvent casting method; buccal films; bio-adhesion; hydration; bioavailability;

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The oral route is one of the most important routes for local and systemic drug delivery due to its large surface area, high permeability and blood flow. Mouth dissolving films are the most advanced oral forms as they are simpler and easier to use than other dosage forms such as Oro-soluble tablets, sublingual tablets. Fast dissolving drug delivery system were rapidly developed in the 1970s as an alternative to capsules, syrups, and tablets for adults and adolescents who have difficulty swallowing conventional oral solid dosage form. The Oro- soluble film dissolves and disintegrates in less than a minute when placed in the mouth without drinking water or chewing. This form allows the drug to skip first-pass metabolism, which improve the bioavailability of the drug. This article provides a comprehensive review on mechanism of action, merits, formulation, evaluation and covering the aspects related to novel fast dissolving techniques.

Last modified: 2024-02-17 00:56:47