A Randomised Prospective Comparative Study for Comparison of Dexmedetomidine and Ketamine vs Propofol and Ketamine for Procedural Sedation in Pediatric Patients Undergoing Minor Cardiac Procedures in Cardiac Catheterization Laboratory

The study compared dexmedetomidine-ketamine vs propofol-ketamine combination for pediatric cardiac catheterization in terms of hemodynamic stability, respiratory variables and recovery time. It concluded that dexmedetomidine-ketamine combination is a safe practical alternative, without any hemodynamic or respiratory effects during cardiac catheterization laboratory procedure but with some delayed recovery. The strength of this study was the adequate sample size, objective measure of outcome of interest, wide range of patient population and randomization of the intervention.