FAST DISSOLVING ORAL THIN FILM :A REVIEW

Fast dissolving oral films (FDOFs) are the most advanced form of oral solid dosage form due to more flexibility and comfort. It is used as a novel approach, as it dissolve rapidly in mouth and directly reaches to the systemic circulation. Fast dissolving oral film drug delivery system is an alternative to tablets, capsules, and syrups for paediatric and geriatric patients who experience in difficulties of swallowing traditional oral solid dosage forms. It improve the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. Oral films provide better drug utilization by by-passing the first pass metabolism, enhance drug bioavailability and mask the bitter taste of the drug. Film formulations are suitable for cough, cold remedies, sore throat, allergenic conditions, nausea, pain and CNS disorders. Present article overview the advancement in the oral dosage forms, application, formulation consideration, method of preparation, evaluation, marketed product and patented technologies of oral fast disintegrating films.