Mycobacterium Kansasii Hypothetical Proteins Capable of Coding EnzymesJournal: Journal of Pharmacy Research (Vol.9, No. 6)
Publication Date: 2015-06-11
Authors : Rajni Mishra Dilip Gore; Avinash Upadhyay;
Page : 359-364
Keywords : Bioinformatics; Enzyme conserved domain; Hypothetical proteins.;
Background: Mycobacterium kansasii known as Nontuberculous mycobacterium is genetically linked to M.tuberculosis. The genome of M. kansasii highlighted several genes coding hypothetical proteins and these were investigated further for functionality. Methods: The results brought up by CDD BLAST, INTERPROSCAN, PFAM and CATH domain search programs facilitated to search inherent enzyme functions based on available conserved domains in several hypothetical proteins. Results and Discussion: M. kansasii showcased 128 probable enzyme coding hypothetical proteins based on conserved domains analysis. Conclusion: Some M. kansasii hypothetical proteins codes for enzymes and possibly may function in cellular metabolism as investigated by insilico approach.
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