Foot drop in a renal transplant recipient A case report and review of literature

Tacrolimus is a potent immunosuppressive agent used in solid organ transplantation.it acts by inhibiting calcineurin phosphatase and inhibits T-lymphocyte activation. Neurotoxicity is a potentially serious toxic effect of tacrolimus which often is under-recognised. Neurotoxicity ranges from tremors and insomnia to seizures and encephalopathy.We describe a 46 yr-old male renal transplant recipient who developed right foot drop after 6 months of renal transplantation due to tacrolimus toxicity which improved after tacrolimus dose reduction