Unsuspected Celiac Disease Severely Affects Levothyroxine Therapy in Hashimoto’s Thyroiditis: a Case Report

Celiac disease (CD) is relatively common in western populations with estimated prevalence of approximately 1%. With the recent availability of sensitive and specific serological testing, many patients who were either asymptomatic or had subtle symptoms had shown CD. Over the past three decades, the pattern of CD presentation has altered. Many CD cases are now detected in adulthood during investigation of problems as diverse as anemia, osteoporosis, autoimmune disorders, unexplained neurological syndromes and infertility. Hashimoto's thyroiditis is a common thyroid disorder where hypothyroidism is treated by levothyroxine therapy. In our case report, we present how levothyroxine absorption was severely affected by celiac disease in a patient with Hashimoto's thyroiditis.