Development of Cuboidal Nanomedicine by Nanotechnology
Journal: Austin Journal of Nanomedicine & Nanotechnology (Vol.2, No. 4)Publication Date: 2014-05-29
Authors : Basavaraj K Nanjwade; Yallappamaharaj R Hundekar; Meghana S Kamble; Teerapol Srichana;
Page : 1-8
Keywords : Cubosomes; Cubic phase; Bicontinuous; Biodegrability; Controlled release;
Abstract
When amphiphilic lipid systems are placed in aqueous environment that will formed self-assembled nanostructured dispersed particles which are expressed as "Cubosomes" whose size ranges from 10-500 nm in diameter and they appear like dots square shaped, slightly spherical in the form of bicontinuous cubic liquid crystalline phase. The discovery of cubosomes is unique story and spans in the field of food science, biological membranes, differential geometry and digestive process. Cubosomal drug delivery system is great potential in melanoma therapy owing to their potential advantage. Recently the research interesting is inducing on cubosomes due to their thermodynamically stable cubic structure, biodegrability of lipids, the ability of encapsulating hydrophobic, hydrophilic, amphiphilic substances is an excellent candidate for targeting and controlled release of drugs, proteins etc. The review article includes manufacturing techniques, characterisation, and applications of cuboidal drug delivery system.
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