A Brief Review On Niosomes
Journal: Journal of Pharmacy Research (Vol.11, No. 5)Publication Date: 2017-05-08
Authors : Siddharth C Jain; D V Gowda; N. Vishal Gupta; P.K. Kulkarni;
Page : 450-458
Keywords : Niosomes; application; preparation;
Abstract
Controlled release drug products are highly used for the formation and maintenance of whichever concentration needed at target site for longer duration of time, and this drug targeting method named as Niosomes. The niosomal vesicles are basically non-ionic surfactant based uni-lamellar (single) or multi-lamellar (multiple) carriers where in an aqueous solution of solute is totally enclosed by a membrane due to the arrangement of surfactant macromolecules as bilayer, thus emerging as a class of novel vesicular systems. Niosomes are currently the major alternative to liposomes as niosome being stable and economic. They potentiate the pharmacological action of the drug molecules by delaying the clearance of the drug from the circulation, shielding the drug from harsh biological environment and restricting the effects only to the target cells. This article aim to provide a brief knowledge about current advances made in niosome drug delivery system, various formulation methods, along with techniques of characterization, its applications and the current research made in the study of niosomes.
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Last modified: 2017-06-08 01:55:15