CLINICAL AND ANTI-INFLAMMATORY EFFECTIVENESS OF COMPLEX TREATMENT WITH ATORVASTATIN IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Journal: Journal of Clinical and Experimental Medical Research(JC&EMR) (Vol.1, No. 4)Publication Date: 2013-12-15
Authors : Prystupa L. N. Murenets N. A. Dominas V. M. Kyrychenko N. N. Shkandala A. Yu.;
Page : 461-465
Keywords : system inflammation; C-reactive protein; cytokines; chronic obstructive pulmonary disease; atorvastatin;
Abstract
We determinated the increase of C-reactive protein and proinflammatory cytokins (IL-6, IL-8, TNF-α)in patients with chronic obstructive pulmonary disease of II and III stages. Application of atorvastatin in addition to basis therapy in patients with chronic obstructive pulmonary disease enhanced the level of anti-inflammatory treatment effectiveness by: faster decrease of C-reactive proteins and proinflammatory cytokins levels. Using these data we can recommend statins to eliminate inflammation and slow down the disease course.
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