ROLE OF HOMOCYSTEINE IN THE DEVELOPMENT OF JUVENILE RHEUMATOID ARTHRITIS

Purpose: to analyze modern scientifi publications devoted to the problem of juvenile rheumatoid arthritis (JRA) and to determine the role of homocysteine in the pathogenesis of the disease and maintenance of chronic inflmmation by activating oxidative stress and inflencing the processes of protein citrullination and carbomуlation. Results. The role of homocysteine in the pathogenesis of JRA is associated with maintenance of chronic inflmmation through the activation of oxidative stress and inflence on the protein citrullination and carbomуlation processes.