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SYNTHESIS, CHARACTERISATION AND ANTIFUNGAL ACTIVITYOF SOME NEWLY SYNTHESISED POLYSUBSTITUTED PYRAZOLES

Journal: Indian Drugs (Vol.54, No. 10)

Publication Date:

Authors : ; ;

Page : 23-29

Keywords : ;

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Abstract

A novel series of polysubstituted pyrazoles were synthesised by the cyclization of (α phenoxy/octyl) acetyl aryl hydrazones in presence of formic acid, by refluxing (α-phenoxy/octyl) acetic acid hydrazide and substituted aryl aldehyde, using C2H5OH as solvent. The newly synthesised compounds were characterised by IR, 1H NMR spectra and also screened for their promising biological activity i.e. antifungal activity.

Last modified: 2017-11-07 13:52:36