Oncogenic Risk of Endometriosis

Endometriosis is a chronic, inflammatory, and estrogen-dependent, with a prevalence of 10% in women of reproductive age; the pathophysiology is explained based on various theories, the most accepted is the retrograde menstruation associated with chronic inflammation, which could be the link between endometriosis and cancer. The symptomatology is characterized by dysmenorrhea, dyspareunia and infertility. Genetic studies provide information on the pathophysiology of epithelial ovarian cancer but there is still much to learn about the cellular origin and the molecular basis of these diseases and their risks. The management of endometriosis is medical and surgical; complete surgical removal of lesions of endometriosis, as well as removal of the affected ovary future decreases the risk of ovarian cancer.