Impact on IVF Outcome Following Pre-IVF Hysteroscopy and Endometrial Scratching

Background: Transvaginal ultrasonography and hysteroscopy are the tools to assess the inner architecture of the uterus. Hysteroscopy is considered to be the gold standard for management of infertile women. The treatment of repeated implantation failure in spite of transfer of good-quality embryos continues to be a dilemma. In India as such very few studies were conducted to see the effect of endometrial injury on the pregnancy outcome, so the current study was conducted to assess the efficacy of hysteroscopy in identifying the uterine pathologies and to assess the pregnancy rate following the endometrial scratching. Methodology: A prospective cohort study was conducted during June 2012 to may 2015 at KJK Hospital, Trivandrum. All patients undergoing IVF in the said duration are scheduled for Pre IVF Hysteroscopy prior to the onset of periods. All the study population had undergone a transvaginal USG and hysteroscopy. Half of the study population (n=175) had underwent endometrial scratching and the occurrence of clinical pregnancy was compared among the group who had not undergone the endometrial scratching. Results: The uterine pathologies which were picked up by hysteroscopy was almost 4 times more than the uterine pathologies reported by USG. The sensitivity (100%) and specificity (85%) was much higher for hysteroscopy when compared with USG. There was a statistically significant difference in the occurrence of clinical pregnancy among the patients for whom endometrial scratching done when compared to those who had not undergone endometrial scratching (p