CLINICAL MORPHOLOGY OF LIVER: MALIGNANT TUMORS

Background. Among focal lesions of the liver, malignant liver tumors (MLTs) are recorded precisely. According to the WHO, MLTs are the fifth most frequent forms of cancer in men and the seventh in women and rank third among the causes of death from malignant neoplasms in the world. The goal is to present the morphological characteristics of MLT diagnosed in the Grodno region. Material and methods. The object of the study was liver biopsy samples obtained by performing aspiration liver biopsy in patients with suspected tumor process, liver fragments excised during surgery, and also - sectional material. Results. The international classification of MLT is presented. According to the classification, the most frequently diagnosed MLT in the Grodno region is described. The examples (pictures) of the main representatives of MLT are presented: primary and secondary, those of epithelial and mesenchymal origin. More detailed characteristics of hepatocellular and cholangiocellular liver cancer are given. Morphological signs of the tumors are indicated when performing differential diagnostics. Conclusions. Qualitative diagnostics of MLT, which is distinguished by a considerable variety, is possible when performing a complex morphological study carried out by experienced specialists using the methods of histological, immunohistochemical, and often ultrastructural analysis. Knowledge of the structural features of MLT will help increase the role of ultrasound and radiation diagnostics in the early stages of MLT.