Antitubercular and Anthelmintic Activity of Triumfetta rhomboidea
Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.1, No. 3)Publication Date: 2018-05-10
Authors : E. Vadivel Shubham G. Arondekar;
Page : 46-48
Keywords : Triumfetta rhomboidea; Antitubercular activity; Mycobacterium tuberculosis; Anthelmintic activity; Endrullus enguinae.;
Abstract
The purpose of this study was investigating experimentally the invitro Anti-tubercular and anthelmintic activity. Antitubercular activity of Triumfetta rhomboidea was investigated against Mycobacterium tuberculosis using Microplate Alamar Blue assay (MABA) and the anthelmintic activity was evaluated on adult Indian earthworms, Endrullus enguinae. Antitubercular activity was performed in eight different concentrations i.e. from 100 to 0.2 μg/ml. Anthelmintic activity was performed in three different concentrations such as 100mg/ml, 50mg/ml and 25mg/ml. Both the activities were dose-dependent. The highest concentration showed the maximum activity. Our results confirm that the methanolic and water extract of Triumfettarhomboidea exhibited significant effect against Mycobacterium tuberculosis and Endrullus enguinae respectively. Antitubercular and anthelmintic activity leads some support to the therapeutic use of Triumfetta rhomboidea for various ailments in the traditional medicine of India.
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