DIAGNOSIS AND TREATMENT OF ACTH-DEPENDENT AND ACTH-INDEPENDENT ENDOGENOUS HYPERCORTISOLISM

The study topicality of the differential diagnosis of various forms of endogenous hypercortisolism is due to the difficulty of topical diagnosis of neuroendocrine tumors of various localization, which produce ACTH, glucocorticoids, despite the significant improvement of existing methods of investigation that determines further treatment. Only a thorough search for the primary source of the tumor, which produces glucocorticoids or ACTH, enables to clearly identify the method of treatment and to significantly reduce subsequently the morbidity and mortality of patients with hypercortisolism.