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Alzheimer's disease As an Autoimmune Disorder

Journal: International Research Journal of Advanced Engineering and Science (IRJAES) (Vol.3, No. 4)

Publication Date:

Authors : ;

Page : 233-237

Keywords : Alzheimer's disease (AD); Amyloid beta (Aβ); Autoimmune Disorder (AD); Lipid Rafts; Ceramide (Cer); Tau protein.;

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Alzheimer's disease could be an autoimmune disorder. Ceramide, the lipid molecules bound to Amyloid beta in cell membrane act as non - magnetic antigens and induce the activation of immune cells. The acid sphingomyelinase releases ceramide from sphingomyelin finally resulting in the formation of ceramide-enriched membrane. platforms. These membrane domains serve the clustering of receptor molecules for immune cells Receptor clustering is associated with cell death signaling pathway.

Last modified: 2018-12-27 21:33:34