Share Your Research, Maximize Your Social Impacts
MECHANISMS AND CLINICAL SIGNIFICANCE OF NEPHROPROTECTIVE ACTION OF SODIUM-GLUCOSE COTRANSPORTER 2 INHIBITORS
Journal: Juvenis scientia (Vol.2019, No. 1)Publication Date: 2019-01-30
Authors : Pchelin I.Y. Vasilkova V.N. Shishkin A.N. Bayrasheva V.K. Hudiakova N.V.;
Page : 4-9
Keywords : DIABETES MELLITUS; ORAL HYPOGLYCEMIC AGENTS; SGLT2 INHIBITORS; CHRONIC KIDNEY DISEASE; DIABETIC NEPHROPATHY; NEPHROPROTECTION;
Source : Download
Find it from : Google Scholar
Abstract
The issue of mechanisms and clinical significance of nephroprotective action of sodium-glucose cotransporter 2 (SGLT2) inhibitors is dealt with. Discussed are the manifestations related to the following effects of the members of this pharmacological group: their influence on glomerular filtration rate, glycaemia, diuresis, ketogenesis and other factors. The results of recent experimental and clinical studies revealing particular aspects of nephroprotective action of SGLT 2 inhibitors in type 2 diabetes mellitus and other pathological conditions are analyzed.
Other Latest Articles
- Seasonal variation of acid phosphatase and dehydrogenase activity in natural and artificial habitats of hazel
- The more knowledge about heterotic loci is a pre-requisite for enhancing grain yield potential in distant crosses
- Wheat (Triticum aestivum L.) mutants throught in vitro selection tolerant on lowland tropic1
- Genetic analysis to determine the nature and magnitude of genetic variances and heritability estimates in maize (Zea mays L.)
- Optimization model of paddlewheel as water quality engineering tool in intensive pond culture of vannamei shrimp (litopenaeus vannamei). in bbap situbondo, east java, Indonesia
Last modified: 2019-03-11 16:20:37