MATHEMATICAL MODELING OF HYDRODYNAMICS IN SINGLE USE BIOREACTOR
Journal: International Scientific Journal "Internauka" (Vol.1, No. 58)Publication Date: 2018-10-31
Authors : Bolila Yelyzaveta; Kostyk Sergii; Ruzhynska Lyudmila; Povodzinskiy Vadim;
Page : 47-51
Keywords : cultivation; single-use bioreactor; mammalian cells; shear stress;
Abstract
The article is devoted to the illumination of modern equipment for the cultivation of mammalian cells. The paper examines existing research, advantages and disadvantages of disposable bioreactors. The authors proposed a new design of the apparatus and created a mathematical model of the process of hydrodynamics. The critical shear stress of mammalian cells for the proposed design is determined.
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