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Effect of Bisphenol A on Some of Antioxidants in White Male Rats

Journal: Scientific Journal of Medical Research (Vol.3, No. 10)

Publication Date:

Authors : ;

Page : 83-86

Keywords : ;

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Abstract

Objectives: The study aimed to determine the effect of bisphenol A on some antioxidants in white male rats. Methods: In this experiment, 24 rats were divided into three groups of 8 replicates per group for 8 weeks. Two groups were treated orally with two different concentrations of bisphenol A, 15 and 30 mg / kg body weight. The control group was treated with corn oil. The effect of bisphenol A on serum GSH, MDA, CAT and SOD, was studied. Results: The results showed an increase in MDA level and a decrease in GSH, CAT and SOD levels in groups treated with bisphenol concentrations compared with control group. Conclusion: These results suggest that BPA exposure might induce oxidative stress and its complications in adult male rats.

Last modified: 2019-06-29 20:21:09