ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH SECONDARY LYMPHEDEMA AND METHODS OF ITS CORRECTION (LITERATURE REVIEW)

Analysis of Russian and international publications is carried out, and a review is presented concerning dysfunction of the endothelium in patients with secondary lymphedema of lower limbs. Increasing attention is given to the condition of endothelium in diseases of cardiovascular system including lymphedema, since impairment of lymph outflow is closely associated not only with structural alterations of the lymphatic system, but also with its functional condition. Despite the research being conducted, no universal concept of the pathogenesis of lymphedema has been created so far. A further study of the basis of development and progression of pathology of lymphatic system is important for elaboration of algorithms of the effective pathogenetic correction and improvement of the quality of life of patients.