Biomechanical analysis of tension-compression asymmetry, anisotropy and heterogeneity of bone reconstruction in response to periprosthetic fracture repair

Bone repair after periprosthetic fracture is a critical issue in orthopedics. Biomechanical analysis given in this review has been concerned with understanding on how mechanical signals and molecular mechanisms affect the healing of Vancouver periprosthetic femoral fracture of B1 and C-type with the use of internal fixation through a less invasive stabilization system (LISS)-plate, which is screwed into the artificial hip joint. The outcome of this analysis will be how the implant/biomaterial interface with bone, translation of mechanical to biological signals and treatment of periprosthetic femoral fractures after total hip arthroplasty with the use of LISS-plates and screws for internal fixation may be controlled in order to improve the fracture healing rate and shorten treatment duration.