Effectiveness of Tahongai (Kleinhosvia Hospita L.) Leaf Extract in Killing Larvae Anopheles sp

Background: Malaria is an infectious disease caused by malaria parasites, which is transmitted to humans through the bite of the Anopheles sp. This disease can attack all races, ages, and genders (Irianto, 2015). The method commonly used today to control mosquito larvae is through the use of chemicals such as abate (Ishak, Dom, Hussain, & Sabri, 2014). This can cause many problems such as insecticide resistance, revival of pest species, environmental pollution, toxic hazards to humans and other organisms. To overcome this problem, many use natural plant-based products as larvicides because they are a rich source of bioactive chemicals (Wahyuni, 2015). Utilization of medicinal plants (herbs) as traditional medicine is one of the efforts to improve the level of public health. The ingredients to make it can also be obtained in nature, are economical, and have no side effects like chemical drugs. One medicinal plant that is often used by people in Indonesia is Tahongai (Kleinhosvia hospita L.). Purpose: To identify the active compound activity of Tahongai Leaf (Kleinhosvia Hospita L.) extracts against larvae of Anopheles sp. Method: This type of research is experimental or experimental and the research design used is quasi experimental post test control group design, where each treatment is given a homogeneous condition so it is expected that there are no factors that affect the anti-larval activity of Anopheles sp. Results: Larvicidal activity of Tahongai extract (Kleinhosvia hospita L.) is a concentration of 0.5 mg / mL with 17 larvae mortality, 1 mg / mL concentration with 22 larvae mortality, concentration of 2 mg / mL larvae mortality of 25 tails, concentration 4 mg / mL with 25 larvae mortality, and at a concentration of 8 mg / mL larvae mortality as many as 25 larvae. Conclusion: Tahongai (Kleinhosvia hospita L.) extract has an active compound of larvaside which can kill Anopheles sp