Synthesis and Atiplatelet of 2-(ethyl amino acid esters), Amino pyridyl 1,3- oxzine
Journal: Journal of Advances in Chemistry (Vol.2, No. 2)Publication Date: 2013-08-07
Authors : Mohamad Alajelee;
Page : 91-97
Keywords : Antiplatelet; 1; 3 oxazine; amino acid esters inhibitory activity;
Abstract
2-(N-glycyl ,Alanyl , leucinyl , isoleacinyl , methionyl , phenyl alanyl, vilinyl methyl ester) , 2-Amino and 4- Amino pyrideyl -1,3- Benzoxazine -4- one were synthesized from the reaction of the corresponding amino acids ester , Amino pyridines with methyl cyano salicylate using improved method. The resulted benzoxazine derivative were tested for their Antiplatelet inhibitory activity , their IR , NMR (1H , 13C) were also studied and checked by elemental analysis.
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