EFFECTIVENESS OF COMPLEX THERAPY OF BENIGN PROSTATIC HYPERPLASIA IN PATIENTS WITH METABOLIC SYNDROME

Benign prostatic hyperplasia (BPH) is a common age-dependent multifactorial urological disease that has important medical and social significance. According to many modern concepts, it is the leading cause of lower urinary tract symptoms in men (LUTS). A certain role in the development and progression of BPH is played by a cascade of metabolically interrelated disorders of carbohydrate and lipid metabolism associated with visceral obesity and arterial hypertension, collectively termed «Metabolic syndrome» (MS). In view of the identified impact of MS on BHP and with the aim to achieve the required effect in treatment of LUTS, to reduce the volume of prostate adenoma, and to improve the quality of life of patients, it is necessary that each component of MS should be corrected timely and in a competent manner. In the article, a clinical case, demonstrating the effectiveness of complex conservative therapy in a patient with BPH/LUTS and concomitant MS, is presented. Use of a strict diet, physical exercise, reduction of body mass, normalization of blood pressure, of lipid profile, correction of carbohydrate metabolism in combination with the administration of tamsulosin permitted to achieve decrease in the prostate volume, reduction of the severity of LUTS and a significant improvement of the quality of his life in a patient with BPH/LUTS. The tactics of managing patients with this comorbid pathology was based on the «Treat to Target» principle.