Study of Highly Sensitive C-Reactive Protein Level in Medical Students with Metabolic Syndrome

Background Metabolic syndrome is considered proinflammatory state, and measurement of inflammatory markers like high-sensitivity C-reactive protein (hs-CRP) can improve the prediction of cardiovascular disease in subject with metabolic syndrome. Methods We prospectively studied the relationship of high-sensitivity C-reactive protein (hs-CRP) with various components of metabolic syndrome in 50 medical students with metabolic syndrome at our tertiary care centre. Results The mean age of patients was 22.18 1.22years, with 26 (52 %) males and 24 (48 %) females. On univariate analysis, hs-CRP was found to be significantly increased in subjects with abnormal waist circumference (p= 0.0001), with deranged fasting glucose levels (p=0.0430) and those with hypertension (p=0.022) There was no significant association between hs-CRP and high triglycerides and reduced high density lipoprotein cholesterol. hs-CRP increased significantly with increasing number of components of metabolic syndrome (p=0.0074) Conclusions High concentration of hs-CRP was present in subjects with metabolic syndrome. Therefore hs-CRP can be used as a maker of inflammation in metabolic syndrome. Metabolic Syndrome, Highly Sensitive C-Reactive Protein, Obesity, Medical students.