Characterization of Hepatobiliary Scintigraphy using Quantification Analysis

Serial scintigraphy images following injection of [99mTc] (IDA) compounds such as [99mTc] diisopropy Hminodiaceticacid (HIDA) provide qualitative information about liver function. We have investigated approaches for quantitatively describing liver function in terms of the kinetics of HIDA extraction and excretion by the liver cell. One hundred and thirty five infants under 12 months of age (65 females and 70 males) were studied in Nuclear Medicine department in Royal care center at Khartoum state during the years 2012-2015, 99mTc HIDA scan was administered intravenously, and images were obtained for up to 24 hours or until gastrointestinal excretion was noted. The result of this study showed that the most effected age was (3 to 6) month. The absorption of radiopharmaceutical (Tc99m HIDA) from 5mint until 35 mint. Shows slight decreases execrations of radiotracer from 35 mint up 60 mint but still more the base count at 5 minute. Hepatobiliary scintigraphy should be used as part of the overall evaluation of neonates and infants with neonatal cholestasis and jaundice