Study of Coagulase Negative Staphylococci Isolated From Clinical Specimens in Tertiary Care Hospital from Western Maharashtra

Coagulase negative staphylococcus is now being increasingly recognized as pathogens. Coagulase negative staphylococci have become a common cause of nosocomial infections, particularly blood stream infections and infections related to prosthesis. The present study was carried out to study the coagulase negative staphylococcus isolated from various clinical specimens and to determine their antimicrobial susceptibility. Methodology-A total of 103 strains of coagulase negative staphylococci isolated in pure form from various clinical specimens were included in the study. All clinical specimens were processed as per the standard laboratory procedures. RESULTS - In present study majority of the isolates were from blood 44 (42.72 %) followed by urine 29 (28.16 %), pus 16 (15.53 %), catheter tip 6 (5.83 %), ETT 5 (4.85 %), and 1 (0.97 %) each from sputum, peritoneal fluid and pleural fluid. Maximum patients were 23 (22.33 %) were in the age group of 21-30 years followed by 51-60 years (15.53 %) and 41-50 yrs 15 (14.56 %). Maximum no. of males 57 (55.34 %) had CoNS infections as compared to females 46 (44.66 %). the maximum sensitivity was seen to Netilmycin 71 (68.93 %) followed by Co-triamoxazole (60.19 %), Amikacin (46.60 %), Cephotaxime (42.72 %). All the isolates were Penicillin-G resistant. Chloramphenicol resistance was observed 74.76 %.