Antibacterial Activities and Biofilm Inhibition of CdS Nanoparticles Prepared from Tri Substituted Imidazolium Ionic Liquids

In this paper, cadmium sulphide nanoparticles were synthesized by a simple and low temperature chemical method using cadmium acetate and thioacetamide precursor in a green solvent, the ionic liquid ( [EBMIM] BF4, [EBMIM]PF6) in a very short time scale. Highly substituted imidazolium based ionic liquids were synthesized and the structures were confirmed by spectral studies such as FT-IR, 1H-NMR and 13C-NMR. The synthesized nanoparticles were characterized by X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM) and Energy dispersive X-ray spectroscopy (EDX), have been emlpoyed for the characterization of size, structure and morphology of the synthesized CdS nanoparticles. Energy dispersive X-ray spectroscopy (EDX) investigations reveal that the products are very pure and nearly stoichiometric. In addition, the antibacterial activity and bio film inhibition of the as synthesized CdS nanoparticles were also tested against S. aureus and P. aeruginosa pathogens by broth dilution method. The results indicate that anionic part of ionic liquids plays an important role in the formation, size and shape of nanoparticles. Nanoparticles synthesized in ionic liquids with PF6- are the most effective products against the tested bacterial strains compared with nanoparticles prepared in ionic liquids with BF4- anion. Compared with two different microorganisms gram negative bacteria is more effective than gram positive bacteria.